Table 1.

Key characterization parameters of liposomes used in the study.

ConcentrationDrug to lipidParticle sizePurity
LiposomesLotDTXp (mg/mL)Phospholipid (PL; mmol/L)DTXp/PL (g/mol)Diameter (nm)PDIDTXp (%)DTX (%)
EphA2-ILs-DTXpTE20155.5615.67354.8110.40.03998.041.96
TC02156.0216.14373.1113.60.03898.951.05
NT-ILs-DTXpTE271511.0330.78358.4108.80.01498.801.20
EphA2-ILsTC2415N/A38.28N/A103.60.039N/AN/A
  • Abbreviations: DTX, docetaxel; N/A, not applicable; PDI, polydispersity index.