Table 1.

Growth inhibition of selected cancer cell lines in the NCI-60 assay and associated SI

GI50 (μmol/L)a
NSCA498K562NCI-H460CAKI-1TK-10RXF 393786-0ACHNSN12CSI
RITA652287b0.0160.600.0560.0120.0290.585.2206.80.10
1773097c0.133129373.957>10039677.9
2773392c0.173873>100>100>100>100>100>1008.2
3777196c0.0146.12.05.00.29139852633.6
4777422c0.0167.01.35.0>1002134>100>1004.5
5778301c0.0200.620.121.20.150.327.264970.24
6782846c0.018129.7410.64806944898.8
Imatinib743414b220.0241634271516253320
  • aGI50 values for all cell lines are provided in the Supplementary Information.

  • bNCI-60 data for NSC 652287 (n = 7) and 743414 (n = 2) are accessible online at https://dtp.cancer.gov.

  • cn = 2.