Table 3.

SLCO2B1 rs12422149 genotype and response to ADT

PopulationTxClinical outcomeResultHRP
mHSPC + BRADTTTP21 m for GG vs. 32 m for AA/AG1.400.018
mHSPC + BRADTTTP20 m for GG vs. 27 m for AA/AG1.310.049
mHSPC + BRADTTTP10 m for GG vs. 17 m for AA/AGN/A0.028
  • Abbreviations: BR, biochemical recurrence; Tx, treatment.