Dose (mg/kg) | AUC (mg*hr/mL) | C_{max} (μg/mL) | V_{ss} (mL/kg) | CL (mL/day/kg) | t_{1/2} (days) | MRT (days) |
---|---|---|---|---|---|---|

1 | 2.6 | 30.3 | 35.9 | 10.5 | 2.8 | 3.9 |

3 | 9.7 | 92.8 | 33.9 | 7.5 | 4.2 | 4.6 |

10 | 47.0 | 395.1 | 35.9 | 5.1 | 4.8 | 7.1 |

30 | 207.0 | 1344.4 | 27.0 | 3.7 | 5.1 | 7.8 |

NOTE: Units: Dose (mg/kg); C

_{max}(denotes the first observed concentrations post IV dosing, μg/mL); V_{ss}(volume of distribution at steady state, mL/kg);*t*_{1/2}(half life, days; harmonic mean); AUC (area under the curve from 0 to infinity, mg*hr/mL); CL (serum clearance, mL/day/kg); MRT (mean residence time, days).