Table 1.

IC50 values (nmol/L) of EGFR-TKIs for Ba/F3 cells harboring EGFR mutations

ErlotinibAfatinibOsimertinibNaquotinib
exon19 del70.769
L858R240.71611
exon19 del+T790M1590176710
L858+T790M>10000821749
exon19 del+T790M+C797S90612141180235
L858+T790M+C797S1910162519131994
Wild-type66728704830