Table 1.

Cox regression survival analysis of the Kocak cohort

Univariate analysisMultivariate analysis
CovariateHR (95% CI)PHR (95% CI)P
MYCN gene amplification9.23 (6.05–14.07)5.4e−254.06 (2.48–6.65)2.5e−8
Stage III/IV9.59 (5.11–18.02)2.1e−123.40 (1.71–6.77)0.001
Age > 18 months9.79 (5.77–16.61)2.7e−173.63 (1.99–6.65)2.8e−5
High PIM1 expression2.14 (1.38–3.31)0.0011.06 (0.65–1.72)0.827
High PIM2 expression2.00 (1.29–3.08)0.0021.06 (0.65–1.73)0.812
High PIM3 expression2.31 (1.49–3.59)2.0e−40.89 (0.53–1.50)0.666
High PIM1, -2, or -3 expression5.29 (2.15–13.03)2.9e−43.05 (1.03–8.97)0.043
  • Abbreviation: CI, confidence interval.