Table 5.

Multivariate survival analysis

OS month
CovariateLevelNMedian survival (m) (95% CI)HR (95% CI)HR P-value
EGFR average overall≤ Median (0.8)47109.8 (90.3, NA)0.77 (0.35–1.69)0.516
>Median (0.8)4390.2 (37.4–187.6)
HER3 average overall≤Median (0.1625)46103.7 (84–187.6)0.89 (0.39–2.03)0.778
>Median (0.1625)44109.8 (22.4, NA)
HER2 average overall068103.7 (90.2–187.6)0.70 (0.29–1.65)0.414
0.025–0.32342.3 (18.6, NA)
PD-L1067101.6 (84, NA)1.06 (0.61–3.01)0.911
1–13023187.6 (45.2–187.6)
PD-L2030109.81.44 (0.61–3.43)-0.406
1–13050103.7
PD-1 positive lymphocytes in tumor0–13390.2 (23.2, NA)1.11 (0.51–2.42)0.797
2–455109.8 (95.8–187.6)
PD-1 positive lymphocytes in peritumoral stroma0–11137 (14.2, NA)3.17 (1.03–9.78)0.045
2–477187.6 (90.2, NA)