Table 1.

Macropinocytosis, FcγRIIA and sensitivity to AGS-16C3F

Megakaryocytes
HSCsWk1Wk2
AGS-16C3F IC50 (nmol/L)16.9 ± 2.241 ± 898 ± 2.4
FcγRIIA expression (MFIR)1.4 ± 0.25.8 ± 2.86.4 ± 2.1
Macropinocytosis (MFIR)14.4 ± 4.75.3 ± 0.4