Table 1.

SNPs and Primers

SNPLocationMAFaBase change (amino acid change)Primer sequence
TLR 1rs5743618Exon 40.25T > GF5′-TGGCACACCATCCTGAGATAC-3′
(missense)R5′-ACCCGGAAAGTTATAGAGGAACC-3′
rs57435655′-UTR0.19T > CF5′-TGGCCTGAGAAACAGAAGGAC-3′
R5′-CCCGCCATTTGTATTCTCTTC-3′
TLR 2rs3804099Exon 30.44C > TF5′-CCTTGAGGAACTTGAGATTGATG-3′
(synonymous)R5′-CCAAACATTCCACGGAACTTG-3′
rs4696480Promoter0.48T > AF5′-ATGGTTCTGGAGTCTGGGAAG-3′
R5′-CCAAGGGAGCAGTTTATTGTGAG-3′
TLR 6rs3821985Exon 10.32G > CF5′-CCTTCGTCATGAGACCTACTTTG-3′
(synonymous)R5′-CTCATGCACCAAGCACATTC-3′
rs5743818Exon 10.27A > CF5′-CCCAGGCAGAATCATGTTCAC-3′
(synonymous)R5′-TTGGATCTGCCCTGGTATCTC-3′
TAK1rs1145727Intron0.30A > GF5′-GCTAAGATGAGAGTCAAGACAGAGAC-3′
R5′-GCTGAGTTAATTCTGACAAAAGGAC-3′
rs1576885′-UTR0.31T > CF5′-TCCTCAAATTAGACAAGGAACAGAG-3′
R5′-AGAAGCCTAGGCCTTAAAGGTG-3′
rs157432Intron0.30T > GF5′-AAGAATGGACCCCTGCCTTC-3′
R5′-GCCTTCATCATTAGCCCTTACC-3′
  • Abbreviation: 5′-UTR, 5′-untranslated region.

  • aMinor allele frequency (MAF), according to the Ensembl database (phase I of the 1000 Genomes Project) for Europeans.