Table 1.

Numbers of mice bearing MDA-MB-231–LM2-4175 xenografts that had lung metastases after treatment with vehicle (control) or selumetinib (50 mg/kg mouse body weight) daily for 3 weeks

Weeks of treatmentGroup of treatmentNumber of mice with metastatic tumorsIncidence of lung metastasis
Week 1Vehicle9/1560
Selumetinib3/1421
Week 2Vehicle9/1464
Selumetinib3/1323
Week 3Vehicle Selumetinib9/14 5/1364 38