Table 1.

Clinicopathologic features of a series of 18 cases (22 samples) of DFSP, including p16/CDKN2A status

CasePatient IDDiagnosisaSexb/ageLocationcPDGFB FISHdp16 expressionCDKN2A FISHRB1 expression
1DFSP-01GCFM/26Groin++++
2DFSP-02DFSPM/23Buttock+ (2–5)+++
3DFSP-03DFSPM/34ForeheadN/A+N/AN/A
4DFSP-04DFSPF/51Buttock+ (1–2)+++
5DFSP-05DFSPF/56Neck+ (2–5)+++
6DFSP-06DFSPF/33R anterior thigh+++
7DFSP-07DFSPM/27Forehead+ (3–5)++
8DFSP-08DFSPF/45Neck/shoulder+ (3–5)N/A+N/A
9DFSP-09DFSPM/38Groin+ (2–4)+++
10DFSP-10DFSPM/47Thigh+ (2–5)+++
11DFSP-11DFSPF/42Abdominal wall+ (1–2)+++
12DFSP-12Hypercellular DFSPM/55L anterior chest wall+ (1–2)Homozygous deletion+
13DFSP-12Hypercellular DFSPM/55L anterior chest wall+ (1–2)Homozygous deletion+
14FS-DFSP-01FS-DFSPF/75Chest wall+ (1–2)++
15FS-DFSP-02FS-DFSPF/36Abdominal wall+ (1)+++
16FS-DFSP-03FS-DFSPM/31L lung metastasis+Homozygous deletion+
17FS-DFSP-03FS-DFSPM/34R lung metastasis+Homozygous deletion+
18FS-DFSP-04FS-DFSPM/49Shoulder+ (3–5)+++
19FS-DFSP-05FS-DFSPM/43Back+ (3–6)++
20FS-DFSP-05FS-DFSPM/44Back+ (3–5)N/A+
21FS-DFSP-06FS-DFSPF/52R lung metastasis+Homozygous deletion+
22eFS-DFSP-06FS-DFSPF/53R breast metastasis+ (3–5)Homozygous deletion+

Abbreviation: N/A, not available.

  • aGCF, giant cell fibroblastoma

  • bM, male; F, female.

  • cL, left; R, right.

  • dPositive/negative (number of copies).

  • eThis case corresponds to the surgical resection from which the cell line DFSP105 was established.