Table 1.

Analyzed SNPs

CategoryGeneSNPs
Metabolisms/detoxification of fluoropyrimidinesThymidylate synthase (TYMS)rs34743033, rs2244500
Dihidropyrimidine dehydrogenase (DPYD)rs3918290, rs6663828, rs970337
Methylentetrahydrofolate reductase (MTHFR)rs1801133, rs1801131, rs6541003
Orotate phosphoribosyltransferase (OPRT)rs1801019, rs3772807
Metabolisms/detoxification of oxaliplatin and DNA repair genesGlutatione S-transferase pi 1 (GSTP1)rs1695, rs749174
Excision repair cross-complementing 1 (ERCC1)rs11615, rs 3212964
Excision repair cross-complementing 2 (ERCC2/XPD)rs1799793, rs 238404, rs13181
Excision repair cross-complementing 5 (ERCC5/XPG)rs4150279, rs4150360
Excision repair cross-complementing 6 (ERCC6)rs2228527, rs7907557
X-ray repair cross-complementing group 1 (XRCC 1)rs25487, rs25489, rs12611088, rs3213255
X-ray repair cross-complementing group 2 (XRCC 2)rs3218536,rs 3218408, rs3111417
RAD23 homolog B (RAD23B)rs2147072, rs10759225, rs1805329
Methylguanine-DNA methyltransferase (MGMT)rs1803965, rs656639
Xeroderma pigmentosum, complementation group A (XPA)rs3176751, rs3176639
Xeroderma pigmentosum, complementation group C (XPC)rs2733534
EGFR pathwayEpidermal growth factor (EGF)rs6824594, rs929446
Epidermal growth factor receptor (EGFR)rs11543848
Akt murine thymoma viral oncogene homolog 1 (AKT1)rs3803304, rs10142069, rs3001371
Akt murine thymoma viral oncogene homolog 2 (AKT2)rs2304186, rs7260517
AngiogenesisVascular endothelial growth factor (VEGF)rs833070, rs3025039
Interleukin 8 (IL8)rs4073, rs2227306
OthersATP-binding cassette, subfamily B, member 1 (ABCB1)rs1045642
ATP-binding cassette, subfamily G, member 2 (ABCG2)rs2231142, rs2728124, rs3114018
Sulfotransferase (SULT1A1)rs1968752
Selectin E (SELE)rs5361, rs3917412, rs3917436
Matrix metalloproteinase 1 (MMP1)rs498186
Matrix metalloproteinase 3 (MMP3)rs602128
Cyclin H (CCNH)rs2230641, rs3093816
Intercellular adhesion molecule 1 (ICAM1)rs3093030
Insulin-like growth factor 1 receptor (IGF1R)rs2229765, rs939626
Mechanistic target of rapamycin (MTOR)rs2295080, rs357278, rs6895953
LSM3 homolog, U6 small nuclear RNA associated (LSM3)rs2607739