Table 2.

Clinical and pathologic characteristics in the training and validation cohorts

CharacteristicsAll patients (n = 379)Training set (n = 202)Validation set (n = 177)P
Median age (range)61.94 (23–85)63.82 (23–85)59.8 (23–76)0.231
Sex
 Men194 (51.18%)115 (56.93%)79 (44.63%)0.068
 Women185 (48.81%)87 (43.06%)98 (55.36%)
Tumor site
 Cecum-right colon115 (30.34%)60 (29.7%)55 (33.07%)0.235
 Transverse colon23 (6.06%)15 (7.42%)8 (4.51%)
 Left colon52 (13.72%)28 (13.86%)24 (13.55%)
 Sigma189 (49.86%)99 (49%)90 (50.84%)
Differentiation
 Grade 160 (15.83%)19 (9.4%)41 (23.16%)0.001
 Grade 2274 (72.29%)160 (79.2%)114 (64.4%)
 Grade 345 (11.87%)23 (11.4%)22 (12.42%)
Stage
 II105 (27.7%)60 (29.7%)45 (25.42%)0.208
 III274 (72.3%)142 (70.3%)132 (74.57%)
Lymphovascular invasion
 Yes164 (43.27%)88 (43.56%)76 (42.93%)0.311
 No215 (56.73%)114 (56.43%)101 (57.06%)
Perineural invasion
 Yes119 (31.39%)73 (36.13%)46 (25.98%)0.025
 No260 (68.61%)129 (63.86%)131 (74.01%)
Bowel obstruction
 Yes89 (23.48%)53 (26.23%)36 (20.33%)0.184
 No290 (76.51%)149 (73.76%)141 (79.66%)
Bowel perforation
 Yes61 (16.1%)41 (20.3%)20 (11.29%)0.012
 No318 (83.9%)161 (79.7%)157 (88.71%)
Type of adjuvant CT
 FOLFOX206 (54.4%)51 (25.24%)155 (87.57%)0.001
 CAPOX173 (45.6%)151 (74.75%)22 (12.43%)