Table 1.
Summary of the IC
50
and IC
90
PAR level inhibitions for each drug in DT40 and DU145 cells
IC
50
, nmol/L
IC
90
, nmol/L
Drug
DT40
DU145
DT40
DU145
BMN 673
4
11
30
71
Olaparib
6
18
80
120
Rucaparib
21
18
100
120