Table 1.

Combinatorial indices (CI) for medulloblastoma cell lines and short-term cultures treated with LBW242 and cisplatin (aor vincristine) at ED50, 75 and 90

Combinatorial index
Cells culturedED50ED75ED90
Daoy0.050.20.69
D2830.450.610.98
UW2280.520.470.43
Daoya0.0910.70.4
R0011.151.11.07
R0291.150.920.91
R0340.360.440.59
R0600.350.240.16
R0260.730.680.64

NOTE: CI was calculated using the Calcusyn program, where a CI < 1 (bold) indicates synergy, CI of 1 (±0.2) indicates an additive effect and CI > 1 indicates an antagonistic effect.