Table 1.

Enzyme selectivity profile of TAK-960 on selected kinases

Kinase% inhibition at 1,000 nmol/LIC50 (nmol/L)
PLK1101.60.8
PLK28816.9
PLK381.850.2
FAK/PTK298.419.6
MLCK/MYLK90.325.6
FES/FPS81.558.2
282 kinases<80