Table 1.

Patient demographics

Characteristics (n = 56)
Age, y
 Median54
 Range23–81
Gender, n (%)
 Men24 (43)
 Women32 (57)
Primary tumor site, n (%)
 Breast14 (25)
 Melanoma13 (23
 Lung (NSCLC)8 (14.5)
 Lung (SCLC)8 (14.5)
 Head and neck7 (12.5)
 Othera6 (10.5)
Brain metastases, n (%)
 Yes41 (73)
 No15 (27)
No. of prior therapies, n (%)
 ≤215 (27)
 3—523 (41)
 ≥618 (32)
Prior radiotherapy, n (%)
 Yes44 (79)
 No12 (21)
ECOG performance status score, n (%)
 012 (21.5)
 135 (62.5)
 29 (16)

Abbreviation: SCLC, small-cell lung cancer; ECOG, Eastern Cooperative Oncology Group.

  • aOther includes hepatocellular carcinoma (n = 2), colorectal (n = 2), cervical (n = 1), and ovarian (n = 1).