Table 1.

The maximum and minimum signal intensities and variance per size of Cy5.5–TRA-8 and Cy3–anti-EMMPRIN antibody distributed on MIA PaCa-2 or PANC-1 cells when the 2 antibodies were used individually or in combination

MIA PaCa-2PANC-1
MaxMinVar/SizMaxMinVar/Size
Individual useTRA-865.5 ± 8.01.7 ± 0.70.64 ± 0.0417.7 ± 5.11.6 ± 0.90.81 ± 0.04
Anti-EMMP25.3 ± 1.67.3 ± 0.52.04 ± 0.1229.7 ± 3.67.0 ± 1.31.28 ± 0.06
P<0.001<0.001<0.0010.058<0.001<0.001
Combined useTRA-862.0 ± 4.52.6 ± 0.40.49 ± 0.0329.1 ± 2.14.5 ± 0.60.69 ± 0.03
Anti-EMMP36.0 ± 2.87.8 ± 0.91.45 ± 0.0726.2 ± 2.28.0 ± 1.31.35 ± 0.06
P<0.001<0.001<0.0010.3350.015<0.001

NOTE: P values for statistical comparison are given.

Abbreviations: Max, maximum signal intensity; Min, minimum signal intensity; TRA-8, Cy5.5-labeled TRA-8; Anti-EMMP, Cy3-labeled anti-EMMPRIN antibody.