Table 4.

Overall best response by dose cohort

GRN1005 dose30 mg/m260 mg/m2120 mg/m2200 mg/m2300 mg/m2420 mg/m2550 mg/m2650 mg/m2700 mg/m2
Overall best response (n = 43)(n = 1)(n = 3)(n = 3)(n = 3)(n = 6)(n = 5)(n = 1)(n = 16)(n = 5)
CR
PR5
SD11122144
PD2216371

Abbreviations: CR, complete response; PR, partial response; SD, stable disease; and PD, progressive disease.