Table 1.

Radiation response of glioblastoma cells upon treatment with BV6 and radiation

Cell line treatment	Plating efficiency [%]	α [Gy⁻¹]	β [Gy⁻²]	LD₅₀ [Gy]	Radiation enhancement ratio	LD₁₀ [Gy]	Radiation enhancement ratio
A172
Mock treated	32.4	0.2274	0.0178	2.54		6.66
DMSO treated	28.6	0.1813	0.0232	2.81		6.79
BV6 [1.5 μmol/L]	1.1	0.0000	1.1488	0.78	3.62	1.42	4.80
T98G
Mock treated	15.7	0.2142	0.0029	3.11		9.53
DMSO treated	16.0	0.1984	0.0050	3.23		9.39
BV6 [1.5 μmol/L]	6.2	0.2738	0.0045	2.43	1.33	7.49	1.25
U87MG
Mock treated	14.2	0.2371	0.0067	2.72		7.94
DMSO treated	13.9	0.2224	0.0080	2.83		8.03
BV6 [1.5 μmol/L]	8.0	0.1905	0.0146	2.96	0.95	7.63	1.05

NOTE: Radiation enhancement ratios at 50% (LD₅₀) and 10% survival (LD₁₀) were calculated by transforming the linear quadratic equation (SF = exp [−α × D − β × D²]) using α and β values of the individual survival curves.