Table 1.

Summary table showing effect of OSI-027 (20 μmol/L) and rapamycin (20 μmol/L) on pAKT (S473) in 12 and 24 cancer cell lines, respectively

Percentage of cell lines showing pAKT (S473)
StimulationNo changeInhibition
Rapamycin (20 μmol/L, 24 h)15/24 (62)6/24 (25)3/24 (13)
OSI-027 (20 μmol/L, 24 h)0/12 (0)2/12 (17)10/12 (83)