Table 1.

Three week tolerability study of S-110 and 5-Aza-CdR with varying schedules

GroupnTreatmentDoseRouteSchedule
16S-11036.6 mg/kgIV3× Q7D
265-Aza-CdR15 mg/kgIV3× Q7D
36S-11018.3 mg/kgIV3× BIW
465-Aza-CdR7.5 mg/kgIV3× BIW
56S-11012.2 mg/kgIV3× TIW
665-Aza-CdR5.0 mg/kgIV3× TIW