Table 3.

Multivariate analysis of biological parameters for TTP and OS

Covariates for TTPHR (95% CI)Wald P
Model including EGFR mutational status (n = 62)
    Histology: others vs BACs1.4 (0.6–3.2)0.47
    EGFR mut: EGFR Wt vs Mut2.1 (1.5–3.9)0.01
    AKT1-SNP4: AA vs GG+GA1.7 (1.0–2.6)0.06
Model excluding EGFR mutational status (n = 94)
    Histology: others vs BACs1.3 (0.7–3.4)0.09
    AKT1-SNP4: AA vs GG+GA3.4 (2.2–5.9)0.04
Covariates for OSHR (95% CI)Wald P
Model including EGFR mutational status (n = 62)
    Histology: others vs BACs1.4 (0.6–3.2)0.47
    EGFR mut: EGFR Wt vs Mut2.1 (1.0–4.3)0.05
    AKT1-SNP4: AA vs GG+GA2.3 (1.2–2.9)0.04
Model excluding EGFR mutational status (n = 94)
    Histology: others vs BACs1.8 (1.0–3.4)0.06
    AKT1-SNP4: AA vsGG+GA4.8 (1.2–6.3)0.02

Abbreviation: HR, hazard ratio.