Table 3.

Comparative potency (GI50 –log10 values) of the five drugs studied across the NCI-60

–log10 GI50FdUMP[10]FdUTopotecanIrinotecan5FU
NSC-697912NSC-27640NSC-609699NSC-616348NSC-19893
Average7.154.645.837.194.89
Minimum4.303.313.615.454.08
Maximum8.305.986.588.076.63
Range4.002.672.962.632.55

Abbreviations: NSC, National Service Center.