Table 1.

Biological functions of tumor biomarkers selected by the modified COXEN algorithm

Network IDNo. of genesTop biological functions
(A) Vorinostat
    114Tissue development, cellular assembly and organization, cellular function and maintenance
    212Cell cycle, cellular growth and proliferation, endocrine system development and function
    37RNA damage and repair; nucleic acid metabolism; DNA replication, recombination, and repair
(B) Velcade
    112Cellular development, organ morphology, reproductive system development and function
    21Cancer, neurologic disease, infection mechanism