Table 1.

Peptibodies competitively inhibit Ang:Tie2 interactions

AgenthAng1 IC50 (nmol/L)hAng2 IC50 (nmol/L)
L1-7(N)>10,0000.064
mL4-30.0223,085
AMG 3866.20.029
Fc>10,000>10,000

Abbreviation: h, human.