Table 4.

P values resulting from statistical testing of qRT-PCR results

GeneAdministration 1Administration 2
Time point 302 (3 h)Time point 303 (24 h)Time point 305 (3 h)Time point 306 (24 h)
J-T test for trend, Plog2 (AUC) P, line of best fitJ-T test for trend, Plog2 (AUC) P, line of best fitJ-T test for trend, Plog2 (AUC) P, line of best fitJ-T test for trend, Plog2 (AUC) P, line of best fit
BCCIP0.180.150.280.990.420.450.640.43
BUB30.350.910.160.190.460.810.0380.014
CALM20.490.30.20.110.0470.0530.30.98
CCNB10.0240.0210.00180.00180.250.120.430.027
CD867.00E-066.00E-070.400.291.10E-054.50E-060.130.98
CDC14B0.0030.00190.080.0160.090.130.0870.48
CES10.830.250.00020.00180.20.30.00490.011
CHN20.0160.0230.610.140.0220.0490.60.66
EGR10.00220.00190.680.757.70E-054.00E-050.00950.003
FLJ443421.90E-071.50E-090.040.172.50E-061.60E-070.710.68
HEXIM10.000120.000530.340.163.60E-052.40E-060.120.0047
JUN0.00590.00620.0790.620.050.00370.440.6
KITLG0.0270.000980.670.110.350.140.950.38
KRAS0.000370.00590.130.140.180.0450.390.6
MAF0.0210.130.0830.180.10.0150.380.19
MAP3K50.00330.000510.220.0740.0810.00840.030.025
MKI672.60E-054.10E-060.080.060.0010.000490.0830.22
NME10.00740.0341.70E-051.80E-060.0490.0880.00120.00056
PAIP10.580.2710.540.640.610.0870.0098
PFAAP50.0390.0160.150.180.0920.0150.580.34
PHDLA10.0060.000410.0650.0540.140.580.620.8
PRDM20.760.970.220.890.370.420.0110.2
SAP300.0480.320.770.880.0430.150.450.36
STAT30.390.120.240.0650.150.110.00280.00025
WEE10.710.80.0220.030.0240.250.30.049

NOTE: Shading: top eight genes; Boldface indicates P ≤ 0.05. J-T, Jonckheere-Tepstra.