Flow cytometric analysis of the whole tumor leukocyte infiltrate
| Percentage of cells per tumor infiltrate (means ± SD*) | Significance (P) | |||
|---|---|---|---|---|
| sl/sl | sl/+ | +/+ | sl/sl versus sl/+ and +/+ | |
| CD 163(ED2)+ macrophages | 9.56 ± 7.21 | 22.08 ± 11.27 | 19.11 ± 12.43 | <0.001 |
| CD4+ T cells | 3.53 ± 1.46 | 3.33 ± 1.85 | 3.57 ± 1.74 | >0.05 |
| CD8+ T cells | 6.34 ± 3.95 | 8.04 ± 22 | 7.34 ± 27 | >0.05 |
| CD161a+ NK cells | 3.45 ± 2.23 | 3.32 ± 2.81 | 4.07 ± 3.65 | >0.05 |
| Granulocytes | 15.21 ± 3.75 | 16.23 ± 82 | 18.42 ± 04 | >0.05 |
↵*Normalized to tumor weight; Student's t test.