Table 1.

EGFR mutation patterns and clinicopathologic features of studied cases

No.SexAgeSSHistologyDfT size (cm)T stageN stageM stagePath stageEGFRKRASExonNucleotide alterationAA changeExonNucleotide alterationAA changeRemarks
E109M53ExADWD31001AQ787R+L858RWT202,606A>GQ787R212,819T>GL858RNovel
E120F63NSADMD2.51001AE709A+G719CWT182,372A>CE709A182,401G>TG719CNovel
E297F71PSADWD31001AT790M+L858RWT202,615C>TT790M212,819T>GL858R
E1283M56SMADNANA4314H870R+L858RWT212,819T>GL858R212,855A>GH870R

Abbreviations: F, female; M, male; SS, smoking status as defined in the previous study (8); Ex, exsmoker; NS, nonsmoker; PS, passive smoker; SM, current smoker; AD, adenocarcinoma; Df, differentiation; WD, well differentiated; MD, moderately differentiated; T, tumor; N, lymph node; M, metastasis; Path stage, pathologic stage; AA, amino acid; NA, not available.