Table 2.

Specific activities of other 5-FU–metabolizing enzymes

HCT-8/PHCT-8/4hFU
UMPK8,400 ± 6005,400 ± 1,200
TP4.8 ± 0.25.1 ± 2.8
TK3.3 ± 1.93.1 ± 2.4
TS24.4 ± 6.915.5 ± 5.8
UP3.8 ± 2.54.9 ± 2.8
UK31.9 ± 9.825.7 ± 9.3
OPRTase10.5 ± 3.712.4 ± 2.0

NOTE: Specific activities of each enzyme are expressed as nmol/mg/h. Samples were measured in triplicates and three independent experiments were done.