Table 2.

Metastatic spread of myogenin-transduced rhabdomyosarcoma cells in Rag2−/−c−/− mice

CellsLung metastasisLiver metastasis
IncidenceMedianRangeIncidenceMedianRange
RD/123/5 (60%)20–175/5 (100%)12574–218
RD/12-Neo23/4 (75%)20–24/4 (100%)134109–229
RD/12-Myog14/5 (80%)20–315/5 (100%)30*23–36
RD/12-Myog32/4 (50%)10–14/4 (100%)60*32–89

NOTE: Mice received 2 × 106 cells i.v. and were sacrificed 10 wk later.

  • *P < 0.05 vs. RD/12 and RD/12-Neo2 (Wilcoxon rank sum test).