Table 2.

Tabulated results for the data as shown in Fig. 6

TreatmentDose (mg/kg or mg/mouse)%TGIEfficacy growth delay (d)P*Tolerability
AWC (g)Mortality (%)
BMS-754807256170.3683−1.50
12.53840.1177−0.80
6.252430.0631−0.40
Cetuximab0.25851411.10
0.12574120.83442.20
'807+cetuximab25+0.2588240.03571.50
12.5+0.2588380.01661.20
6.25+0.2586230.07191.40
25+0.12589210.20530.60
12.5+0.12586300.22460.40
6.25+0.12579200.29451.20

NOTE: See Materials and Methods for experimental details.

  • *P values were for probability for delay of tumor growth (in days) to the target size of 500 mg.