Table 1.

Top 50 compounds associated with BRAF mutation

NSC IDChemical nameNominal PAdjusted PMean fold difference
676879Phenothiazine, 2-azido-10-[4-(4-methyl-1-piperazinyl)butyl]-difumarate2.30E-071.80E-035.6
46061Phenothiazine, 10-[3-(4-methyl-1-piperazinyl)propyl]-2-(trifluoromethyl)-, disuccinate5.70E-072.20E-035.5
658874No name4.80E-061.20E-026
644902Benzo[b]naphtha[2,3-d]furna-6,11-diome, 4-chloro-3-hydroxy3.30E-052.10E-025.7
708550No name3.10E-052.10E-025.5
661193Propanamide, 2-[4-[[4-chlorophenyl]carbonyl]-2-chlorophenoxy]-2-methyl-N-[2-(dimethylamino)ethyl]1.20E-052.10E-025.5
6789321H-Benzimidazole-4-carboxamide, N-[2-(dimethylamino)ethyl]-2-(4-pyridinyl)-, hydrochloride2.80E-052.10E-025.7
6584432-Chloro-3-amino-5,8-dihydroxy-1,4-naphthoquinone1.90E-052.10E-025.8
717507No name1.40E-052.10E-024.7
715767No name1.90E-052.10E-025.2
689620No name2.20E-052.10E-025.6
664565No name2.80E-052.10E-024.6
6264821,5,10-Trihydroxy-7-methoxy-3-methyl-1H-naphtho[2,3-c]pyran-6,9-dione5.80E-052.30E-026.3
6863241-Methyl-3-(4-[2-dimethylaminoethoxy]phenyl)-2-phenylindolizine6.00E-052.30E-025.6
17474Phenothiazine, 10-[3-(4-methyl-1-piperazinyl)propyl]-2-(trifluoromethyl)-dihydrochloride4.90E-052.30E-025.6
708551No name5.30E-052.30E-025.2
303612Mequitazine6.30E-052.30E-025.6
718579No name5.80E-052.30E-025.6
6769633-Azido-10-[4-(4-(4-benzoylphenyl)methyl)-1-piperazinyl)butyl]phenothiazine, bismaleate salt4.30E-052.30E-025.6
7068291,6-Bis[4-(4-aminophenoxy)phenyl]diamantine5.00E-052.30E-026.1
715580No name5.60E-052.30E-024.8
6619412-(3-Chloropropyloxy) naphthazarin7.20E-052.50E-026.5
6614162-(2-(2-Methoxyethoxy)ethoxy)naphthazarin7.50E-052.50E-026.3
354462Hypothemycin9.50E-053.00E-026.6
635366No name1.10E-043.30E-025.6
707847No name1.00E-043.30E-024.6
6769311-Amino-2-hydroxy-3-naphthoic acid hydrochloride1.10E-043.30E-024.7
708073No name1.20E-043.50E-024.7
6773952-Azido-10-[(4-dimethylamino)butyl]phenothiazine, oxalate salt1.40E-043.70E-025.7
656204Discorhabdin G1.50E-043.70E-025.6
721393No name1.50E+043.70E-025.6
699452No name1.50E-043.70E-025.6
627991Benzo[g]pteridine-2,4-dione,8-chloro-10-(4-chlorophenyl)-3-methyl-1.60E-053.80E-025.6
79563No name1.60E-053.80E-024.6
617131No name1.70E-053.80E-025.7
674092Quinoline-4-carboxamide,N,N′-[(1,4-piperizinediyl)bis(3,1-propanediyl)]bis(2-phenyl-,dihydrochloride1.70E-053.80E-025.4
6822232H-Pyrano[3,2-g]quinoline-5,10-dione,4-hydroxy-2,2,6-trimethyl-1.90E-044.00E-025.7
708864No name1.90E-044.00E-024.7
717827No name2.00E-044.10E-024.3
669995No name2.10E-044.20E-025.4
6584502-Acetamido-6-methyl-8-hydroxy-1,4-naphthaquinone2.60E-044.80E-025.6
649750No name2.50E-044.80E-024.7
90829No name2.90E-045.10E-024.8
681603No name2.90E-045.10E-024.7
713546No name2.80E-045.10E-025.5
707452No name3.00E-045.10E-024.7
708075No name3.10E-045.20E-025.6
13028No name3.30E-045.40E-025.6
689078No name3.50E-045.70E-025.5
656211No name4.00E-046.10E-025.6
  • NOTE: NSC ID, chemical name, Wilcoxon nominal P values, and FDR-adjusted P values of the top 50 compounds associated with BRAF mutation.