Table 1.

3-h biodistributions (%ID/g) of labeled cMORF effector in tumored mice pretargeted 48 h earlier by one of the MORF-MN14, MORF-CC49, and MORF-B72.3 antibodies

OrganMN14CC49B72.3
Liver0.84 ± 0.150.63 ± 0.081.35 ± 0.24
Heart0.55 ± 0.090.30 ± 0.050.85 ± 0.24
Kidney4.10 ± 1.333.57 ± 0.713.41 ± 0.48
Lung0.85 ± 0.160.68 ± 0.061.38 ± 0.41
Spleen0.44 ± 0.060.41 ± 0.050.77 ± 0.15
Muscle0.33 ± 0.190.18 ± 0.030.45 ± 0.13
Tumor6.28 ± 1.476.16 ± 0.478.89 ± 1.28
Salivary gland0.59 ± 0.110.44 ± 0.071.02 ± 0.24
Blood2.26 ± 0.381.60 ± 0.093.75 ± 0.99
Tumor size (g)0.50 ± 0.090.54 ± 0.110.43 ± 0.23