Table 1.

Patient demographics by CYP1B1*3 genotype

CharacteristicDocetaxel-treated cohort
Suramin/thalidomide-treated cohort
AllWT or HetVarAllWT or HetVar
Baseline screening
Total entered52421014511233
Age (y)68 (41-80)66 (41-80)65 (77-73)65 (43-93)65 (43-93)63 (51-88)
Body surface area (m2)2.0 (1.5-2.5)2.0 (1.7-2.5)2.0 (1.8-2.5)2.1 (1.4-2.4)2.1 (1.4-2.3)2.0 (1.7-2.5)
Gleason score*8 (1-10)8 (1-10)8 (7-9)7 (3-10)7 (3-10)8 (5-10)
  • NOTE: Continuous data are given as median with range in parentheses, and categorical data are given as number of patients with percentage of the total population in parentheses. CYP1B1*3 genotype: WT, wild-type; Het, heterozygous variant; Var, homozygous variant.

  • * Gleason scores for two patients were unavailable.