Table 2.

IC50 values for KLM155 against the esophageal cancer cell lines WHCO1 and WHCO6, the nonmalignant breast epithelial cell line MCF12, and the cervical carcinoma cell lines ME180 and SiHa

Cell lineIC50 (μmol/L)95% Confidence interval
WHCO19.59.4–9.5
WHCO65.85.6–6.0
MCF1232.031.6–32.3
ME18033.933.7–34.1
SiHa>150
  • NOTE: Cells were treated with a range of concentrations of each compound, and final cell number was determined using the MTT assay.