Table 4.

NSC (AMID) counts for the NCI-60 tumor classes, derived by panel sensitivity and two-dimensional structural features

Tanimoto score
1.00.90.80.70.60.5
Leukemia1 (1)5 (3)8 (3)11 (4)33 (6)153 (8)
Lung0 (0)4 (1)5 (2)6 (3)7 (3)16 (7)
Colon0 (0)2 (1)3 (2)5 (3)10 (5)22 (6)
CNS2 (2)9 (2)30 (2)32 (2)39 (6)53 (8)
Melanoma0 (0)5 (2)9 (3)12 (3)23 (5)64 (6)
Ovarian0 (0)1 (1)2 (1)4 (3)5 (3)15 (5)
Renal0 (0)0 (0)0 (0)0 (0)4 (3)4 (3)
Prostate0 (0)2 (1)3 (1)3 (1)6 (4)12 (6)
Breast0 (0)2 (2)4 (2)4 (2)3 (5)12 (9)
Totals3 (3)30 (13)64 (16)77 (21)130 (44)351 (58)
Hit rate0.01 (0.05)0.09 (0.22)0.18 (0.28)0.22 (0.36)0.37 (0.76)1.0 (1.0)
  • NOTE: NSC (AMID) counts derived from the complete set of NCI-60 screening data using NCI-60 panel selectivity and two-dimensional structural filters as described in the text. See the legend to Table 1 for additional details.