Table 2.

NSC (AMID) counts for the NCI-60 tumor classes, filtered by panel sensitivity

Tanimoto score
1.00.90.80.70.60.5
Leukemia9 (8)18 (12)24 (12)42 (15)112 (18)410 (23)
Lung6 (6)68 (11)133 (14)154 (19)189 (22)353 (26)
Colon3 (3)14 (5)27 (7)46 (9)103 (9)233 (13)
Brain6 (5)20 (5)65 (5)73 (8)97 (10)188 (12)
Melanoma2 (2)22 (6)44 (6)61 (7)83 (10)209 (10)
Ovarian7 (6)14 (6)37 (8)48 (9)89 (9)212 (10)
Renal1 (1)9 (3)14 (3)17 (3)23 (7)56 (10)
Prostate2 (2)14 (4)19 (6)21 (8)44 (13)158 (17)
Breast6 (5)60 (9)102 (12)155 (14)320 (18)278 (23)
Totals42 (38)239 (61)465 (73)617 (92)1,060 (116)2,097 (144)
Hit rate0.02 (0.26)0.11 (0.42)0.22 (0.51)0.29 (0.64)0.51 (0.81)1.0 (1.0)
  • NOTE: Counts for NSCs (AMIDs) at different Tanimoto cutoffs across the nine cancer classifications. Numbers are based on those NSCs passing threshold filters for differential GI50 profiles (coefficient of variation ≥0.08 and within-panel sensitivity above profile average). As in Table 1, each cancer trial (i.e., row) is processed separately, and the row “Totals” reflect cumulative AMID and NSC counts.