Table 1.

Protein expression pattern (pg/mL) assessed in the ascites of tumor-bearing mice as measured using ELISA or Meso Scale multiplex assay

Parental (pg/mL)Mock (pg/mL)MIF RNAi (pg/mL)P value (parental versus MIF RNAi/mock versus MIF RNAi)
KC421.6 ± 80.42510.3 ± 85.64101.3 ± 77.290.0076/0.0036
VEGF499 ± 112.6444.3 ± 113192.4 ± 48.560.0123/0.0239
MIF188.4 ± 24.35169.5 ± 18.0151.37 ± 27.790.003/0.0035
TNF-α174.9 ± 44.06214.8 ± 53.4390.5 ± 15.070.0349/0.0179
IL-667.07 ± 17.7278.2 ± 23.8610.83 ± 2.6840.0056/0.0083
IL-53.536 ± 0.9242.918 ± 1.1063.881 ± 3.4790.8762/0.6715
IL-10377.9 ± 88.85396.9 ± 91.59468.8 ± 115.40.3408/0.446
IL-121,506 ± 62.951,309 ± 356.22,448 ± 62.160.0001/0.0055
IL-1786.3 ± 23.5476.21 ± 31.5283.21 ± 22.190.872/0.761
  • NOTE: Mean values (±SD, pg/mL) from three time-matched mice in each group are shown.