Combination indices calculated for dose-response curves for combination studies described in results and shown in Figs. 2 and 3
| Cell lines | Combination indices | ||||
|---|---|---|---|---|---|
| ED50 | ED76 | ED90 | |||
| FLT3-ITD-Ba/F3 (LBW242 + PKC412) | 0.74780 | 0.58808 | 0.47158 | ||
| A627T-Ba/F3 (LBW242 + PKC412) | 055582 | 0.40946 | 0.36244 | ||
| F691l-Ba/F3 (LBW242 + PKC412) | 0.63409 | 0.43267 | 0.30145 | ||
| G697r-Ba/F3 (LBW242 + PKC412) | 0.39783 | 0.43210 | 0.47464 | ||
| FLT3-ITD-Ba/F3 (LBW242 + doxorubicin) | 0.89723 | 0.81295 | 0.73688 | ||
| A627T-Ba/F3 (LBW242 + doxorubicin) | 0.38613 | 0.35638 | 0.35964 | ||
| FLT3-ITD-Ba/F3 (LBW242 + Ara-c) | 0.60784 | 0.45149 | 0.33535 | ||
| F691l-Ba/F3 (LBW242 + Ara-c) | 0.60377 | 0.47024 | 0.41785 | ||