Table 1.

Cytotoxic effect of doxorubicin and cisplatin on SAOS-2 and HOS cells

IC50 (μmol/L)
DoxorubicinCisplatin
SAOS-20.061.1
SAOS-2-DsRed20.051.3
SAOS-2-GSTP1-DsRed20.13*2.5*
HOS0.161.8
HOS-control0.151.5
HOS-339si-30.060.7
HOS-339si-60.050.75
  • * Differences between SAOS-2-GSTP1-DsRed2 and SAOS-2 or SAOS-2-DsRed2 were considered statistically significant at P < 0.05.

  • Differences between HOS-339si and HOS or HOS-control were considered statistically significant at P < 0.05.