Table 2.

Sensitivity to Aplidin, vinblastine, and flavopiridol of WT and p27−/− MEFs

DrugWT (IC50 nmol/L)p27−/− (IC50 nmol/L)
Aplidin2.9 ± 0.7*0.5 ± 0.1
Vinblastine7.814
Flavopiridol1.1 × 103>100 × 103
  • * Results are the mean ± SD of five independent experiments.