Table 1.

Inhibition of human cancer cell line proliferation in PI assay, a comparison

Human tumor cell linesP276-00 (μg/mL)
Cisplatin (μg/mL)
IC50IC70IC50IC70
Colon
    CCL DLD10.130.226.3517.29
    CCL HCT-1160.120.201.083.31
    CCL HT-290.132.077.2328.03
    CXF 94L0.060.14>30>30
Gastric
    GXF 251L0.771.616.6919.54
Lung
    LCL H-4600.400.961.222.44
    LXFA 629L0.130.253.9123
    LXFL 529L0.340.905.4015.77
Breast
    MACL MCF-70.140.268.0472.12
    MAXF 401NL0.090.160.632.00
Melanoma
    MEXF 462NL0.120.201.713.63
    MEXF 514L0.220.631.754.84
Prostate
    PRCL PC3M0.931.93>30>30
Renal
    RXF 486L0.871.6740.00>30
    RXF 944L0.160.331.192.20
Uterus
    UXF 1138L0.190.5120.6740.68
Mean0.24 (0.55 μmol/L)0.50 (1.1 μmol/L)4.93 (16 μmol/L)11.94 (40 μmol/L)