Table 3.

Fluorescence-activated cell sorting analysis of cell cycle phases in HDF and H460 lung adenocarcinoma cells treated with compound 1

Cell cycle phaseTreatment (╬╝mol/L)HDF (% singlet cells)
H460 (% singlet cells)
24 h48 h72 h24 h48 h72 h
G1Control57.072.885.645.550.958.2
154.255.366.227.38.92.5
321.111.35.67.87.53.7
SControl13.24.73.623.218.517.8
110.27.46.718.224.32.8
34.25.98.08.48.03.6
G2-MControl22.614.38.219.822.518.2
127.627.021.633.011.210.6
365.661.252.737.714.44.7
Sub-2NControl0.20.50.74.02.52.1
10.30.91.311.614.416.0
30.22.39.124.120.330.0
>4NControl2.43.01.41.20.90.9
13.56.43.55.129.058.6
36.011.219.16.235.951.0