Table 1.

Median and range of carboplatin, cisplatin, daunorubicin and etoposide IC50s in Yoruban and CEPH

DrugYoruban
CEPH
Female (μmol/L)Male (μmol/L)Female (μmol/L)Male (μmol/L)
Carboplatin*,†29.1 (15.3–141.1)24.6 (11.8–70.3)20.4 (10.4–49.2)20.1 (8.6–70.4)
Cisplatin†7.0 (2.2–37.4)6.0 (2.2–27.1)5.2 (1.8–25.8)5.1 (1.5–73.9)
Daunorubicin*0.05 (0.02–0.87)0.05 (0.02–0.27)0.04 (0.01–0.23)0.04 (0.01–0.30)
Etoposide‡0.47 (0.10–17.89)0.37 (0.09–5.38)0.43 (0.04–7.00)0.46 (0.11–17.31)

  • ↵* Statistically significant difference between Yoruban and CEPH.

  • ↵† Statistically significant difference between female and male in Yoruban.

  • ↵‡ Statistically significant difference between female and male in CEPH.