Table 2.

Modulation of P-gp expression level by flow cytometry

Time exposureP-gp expression (%)*
MCF7
MCF7 ADR
1 d2 d1 d2 d
Control100100100100
PBS (nmol/L)
    1553 ± 3.539 ± 4
    2575 ± 370 ± 4
    5070 ± 553 ± 4.650 ± 2.624 ± 4.2
    10064 ± 3.441 ± 2.942 ± 2.812 ± 2.1
  • NOTE: Percent P-gp expression in cells treated with various concentration of PB28 in function of time exposure.

  • * Mean ± SE of three independent experiments.