Table 1.

PB28 affinity and activity evaluation in membrane preparations and in living cell lines

Cell lineKi ± SE (nmol/L)*
IC50 ± SE (nmol/L)*
σ2σ1Exposure time
1 d2 d
MCF70.28 ± 0.0113.0 ± 2.5>>10025 ± 1.3
MCF7 ADR0.17 ± 0.0510.0 ± 0.80>>10015 ± 0.9
  • * Mean ± SE of three independent experiments.