Table 1.

In vivo efficacy of PIA23 in hollow fiber assays

i.p.s.c.
H5222
UACC-62
U251
H2324
MDA-MB-231
SW62022
MDA-MB-43544
OVCAR-52
SF-29542
LOX2
COLO205
OVCAR32
Total1616
  • NOTE: A score of 2 indicates that growth was inhibited ≥50% within the fiber for a particular dose. The number 4 indicates it decreased growth ≥50% in hollow fibers in mice that received both the 25 and 37.5 mg/kg dose levels.