Estimated coefficients ([thetas]p) in prediction formulae for clinical response to platinum/paclitaxel chemotherapy (ln[PFS] = xi1[thetas]1 + xi2[thetas]2 + … + xip[thetas]p + εi)
| xip | [thetas]p | P | ||
|---|---|---|---|---|
| Formulae using expression data of genes known as sensitivity determinants | ||||
| ln[IL6] | 0.203 | 0.056 | ||
| ln[BCL2] | −0.081 | 0.496 | ||
| ln[VEGF] | 0.664 | 0.001 | ||
| ln[ERCC2] | −1.479 | <0.0001 | ||
| ln[ABCB1] | 0.337 | 0.023 | ||
| εi | 6.124 | |||
| Formulae using expression data of genes selected as novel markers | ||||
| ln[MYO5C] | 0.300 | 0.224 | ||
| ln[SPINK1] | −0.170 | 0.114 | ||
| ln[ARMCX3] | −0.818 | 0.115 | ||
| ln[PLEK2] | −0.059 | 0.843 | ||
| ln[PRSS11] | 0.495 | 0.087 | ||
| ln[TNFSF13B] | −0.613 | 0.034 | ||
| ln[IFIT3] | 0.843 | 0.096 | ||
| ln[BTN3A2] | −0.340 | 0.290 | ||
| εi | 6.340 | |||