Table 1.

Treatment response summary for MCF-7 and MDA-MB-231 studies

AgentMDA-MB-231
MCF-7
MTV ± SD (n) on day 18, mm3No. PRsNo. CRsNo. LTTFS*MTV ± SD (n) on day 18, mm3No. PRsNo. CRsNo. LTTFS*
Saline557 ± 209 (10)011488 ± 280 (10)000
Paclitaxel6 ± 7 (10)4620 ± 0.2 (10)095
Epoetin α637 ± 203 (10)000482 ± 178 (10)000
Darbepoetin α548 ± 153 (10)000591 ± 226 (10)000
Epoetin β541 ± 263 (10)000458 ± 195 (10)000
Paclitaxel/epoetin α3 ± 2 (10)1943 ± 6 (10)064
Paclitaxel/darbepoetin α4 ± 4 (10)46211 ± 34 (10)153
Paclitaxel/epoetin β6 ± 7 (10)5311 ± 4 (10)161
  • Abbreviations: MTV, mean tumor volume; n, number of mice; LTTFS, long-term tumor-free survivors.

  • * Mice classified as CRs at the end of the study.